HERBA SIDERITIS: A PUTATIVE ADAPTOGEN FOR REDUCING THE RISK OF AGE-RELATED COGNITIVE DECLINE AND NEURODEGENERATIVE DISORDERS

Herba Sideritis: A putative adaptogen for reducing the risk of age-related cognitive decline and neurodegenerative disorders

Background: Traditional use of Greek mountain tea (GMT), Herba Sideritis (Sideritis scardica Griseb.), is used to treat the common cold and mild gastrointestinal disorders.Recent studies suggest its potential efficacy for reducing the risk of age-related cognitive decline and neurodegenerative diseases, which could be associated with the common mec

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Modeling the effect of time delay in the increment of number of hospital beds to control an infectious disease

One of the key factors to control the spread of any infectious disease is the health care facilities, especially the number of hospital beds.To assess the impact of number of hospital beds and control of an emerged infectious disease, we have formulated a mathematical model by considering population (susceptible, infected, hospitalized) and newly c

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Development of a high-throughput screen to identify small molecule enhancers of sarcospan for the treatment of Duchenne muscular dystrophy

Abstract Background Duchenne muscular dystrophy (DMD) is caused by loss of sarcolemma connection to the extracellular matrix.Transgenic overexpression of the transmembrane protein sarcospan (SSPN) in the DMD mdx mouse model significantly reduces disease pathology by restoring membrane adhesion.Identifying SSPN-based therapies has the potential to b

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